Aggressivecentralgiantcellgranuloma:three-dimensional reconstructionandplanning with autogenous graft. Case report and literature review

Giant Cell Lesions are a group of benign, non-odontogenic intraosseous lesions characterized by the presence of multinucleated giant cells. These lesions can be classified as either aggressive or non- aggressive based on their clinical and radiographic features. The aggressive variant is a rapidly growing lesion that may lead to root resorption, tooth displacement, thinning or perforation of the cortical bone, and is associated with a high recurrence rate. In contrast, the non-aggressive variant is typically asymptomatic, grows slowly, and has a low rate of recurrence. This case describes a 43-year-old male patient diagnosed with an aggressive variant of a mandibular Giant Cell Lesion. The patient was successfully treated with block resection and reconstruction using an iliac crest graft at the Military Hospital of Santiago. For this procedure, virtual planning software and 3D printing technology were employed to design and accurately position a cutting guide and tu- mor resection template, enabling complete preservation of the Inferior Alveolar Nerve (IAN) during surgery. After a one year follow-up, the patient showed favorable progress with no signs of recurrence, and osseointegrated implants were successfully placed. This case underscores the significance and potential of 3D virtual planning in mandibular resection, as it facilitates the preservation of critical anatomical structures that were previously difficult to protect. The integration of advanced technologies such as 3D printing and virtual planning not only enhances surgical precision but also improves clinical outcomes, reduces complications, and elevates the patient's quality of life.