Cemento ossifying fibroma (COF) is a benign fibro-osseous lesion, which occurs mainly in women, between the 3rd and 4th decade, affecting the posterior mandibular region. In this article, an atypical presentation of COF is presented synchronously with a supernumerary tooth included in the maxilla, and a review of the literature is carried out. A 17-year-old male patient, with a radiographic finding of a supernumerary tooth included and an asymptomatic increase in vestibular volume in the maxilla, which causes den- tal malposition. Extraction of the supernumerary tooth and excisional biopsy of the vestibular lesion were performed under local anesthesia. The histopathological study reports a fibro cellular tissue with calcifications similar to bone trabeculae, compatible with Central Ossifying Cement Fibroma. The etiology of COF is uncertain and its mechanism is still unknown, but it could have a genetic or traumatic component as a triggering factor. The literature shows limited reports presented in the maxilla, its characteristics are summarized in this article. A presentation of OFC simultaneously with supernumerary teeth has not been reported, however, it has been presented in conjunction with other injuries or multiple COF.