The literature suggests posterior crossbite as a risk factor for the development of maxillomandibular developmental disorders. However, the results of these studies are heterogeneous and outdated, which prevents asserting the influence of this malocclusion on the craniofacial system. The aim was to collect available information regarding the influence of posterior crossbite on the skeletal, articular and neuromuscular systems to establish general conclusions about its association and lay the foundations for the generation of new studies that allow the development of protocols and evidence-based decisions. A search of the literature was carried out in Pubmed, Scopus, Cochrane and Epistemonikos databases, with the strategy: crossbite AND temporomandibular OR asymmetry NOT orthognathic, contemplating studies from 2013 to 2023. A total of 2,852 articles were collected, of which 14 studies met the established inclusion criteria. The posterior crossbite would have a positive relationship for the development of asymmetries in both musculature and bone structures such as the jaw and structures relevant to the temporomandibular joint. More studies are needed that use complementary tests as a method of diagnosis/ analysis that reduce the overlapping of structures and distortion, thus reducing the possibility of error, in this way it is possible to standardize the results obtained and establish reliable conclusions to be used in clinical practice.